IBRI is poised to transform life sciences—and for millions of people, even life itself.

The Opportunity:

IBRI is seeking a strategic technology leader to join our team as an Enterprise Systems Director. This is responsible for aligning enterprise software, systems, and infrastructure with organizational goals, and oversees IT billing operations, leads Microsoft and AWS solution development, drives integration and automation, and champions innovation through AI, analytics, and change management. A critical focus includes protecting intellectual property, managing external vendors, and ensuring the reliability and security of all IT assets—including software, hardware, and meeting room technology.

This position includes direct report responsibilities.

Responsibilities:

Enterprise Systems Strategy & Alignment

• Develop and execute a roadmap for enterprise software and systems aligned with business objectives.
• Ensure interoperability and integration across platforms to support seamless operations.
• Lead modernization efforts and enterprise architecture planning.

Microsoft & AWS Solutions Development

• Design and implement Microsoft 365, Teams, SharePoint, Power Platform, and Azure-based solutions.
• Develop custom applications and automated workflows using Microsoft technologies.
• Architect and manage AWS cloud infrastructure and services.
• Ensure high availability, performance, and security across cloud environments.

IT Billing & Financial Operations

• Oversee IT billing, invoicing, and financial tracking.
• Manage vendor contracts, renewals, and service agreements.
• Reconcile IT expenditures and ensure budget alignment.
• Maintain documentation of billing records and financial reports.
• Identify cost-saving opportunities and automation strategies.

AI Integration & Analytics

• Lead adoption of AI tools to enhance decision-making and efficiency.
• Oversee dashboard and reporting tool development (e.g., Power BI).
• Ensure data accuracy and accessibility for business intelligence.

Systems Integration & Data Management

• Ensure seamless integration of enterprise applications and data sources.
• Improve data flow, system interoperability, and reporting capabilities.
• Support enterprise architecture planning.

Intellectual Property Protection & System Security

• Implement security protocols to protect proprietary data.
• Collaborate with legal and compliance teams on regulatory obligations.
• Conduct risk assessments, vulnerability scans, and security audits.
• Lead incident response and remediation efforts.
• Stay current with cybersecurity trends.

External Vendor Management

• Manage relationships with IT vendors, consultants, and service providers.
• Evaluate vendor performance and ensure SLA compliance.
• Oversee vendor onboarding, contract negotiations, and renewals.
• Ensure vendors support strategic goals and deliver value.

Technology Oversight & Asset Management

• Oversee all IT software, hardware, and infrastructure assets.
• Manage lifecycle planning, procurement, and maintenance.
• Ensure functionality and support for meeting room technology.
• Coordinate upgrades, troubleshooting, and user support.

Change Management & User Adoption

• Develop and implement change management strategies.
• Promote user adoption through training and communication.
• Collaborate with stakeholders to ensure smooth transitions.

Leadership & Collaboration

• Lead and mentor a team of architects, developers, analysts, and support staff.
• Provide direct supervision, performance management, and professional development.
• Foster cross-functional collaboration to align technology with strategic goals.
• Represent IT in enterprise planning and governance forums.

Qualifications:

• Bachelor’s or master's degree in IT, Computer Science, or related field.
• 7+ years of progressive experience in enterprise systems leadership, cloud infrastructure, Microsoft solution development, and security solutions.
• Expertise in Microsoft 365, Teams, SharePoint, Power Platform, Azure, AWS, and Artic Wolf (or similar security solution).
• Proven experience in IT billing, financial operations, and vendor management.
• Strong understanding of enterprise architecture and system interoperability.
• Experience with AI tools, analytics platforms, and change management.
• Demonstrated success in implementing security frameworks.
• Experience in managing IT hardware, AV systems, and meeting room technology.
• Excellent leadership, communication, and strategic planning skills.
• Microsoft Certified: Azure Solutions Architect, Power Platform Solution Architect, or Teams Administrator (preferred).
• AWS Certified Solutions Architect – Associate or Professional (preferred).
• CISSP or equivalent cybersecurity certification (preferred).
• ITIL Foundation or higher (preferred).
• PMP or equivalent project management certification (preferred).
• Certifications in AI, data analytics, or financial management (optional but beneficial).

Compensation:

Competitive salary and comprehensive benefits offered commensurate with experience.

Equal Employment Opportunity:

The IBRI provides equal employment opportunities to all employees and applicants and does not discriminate based on age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.

About Us:

The Indiana Biosciences Research Institute (IBRI) is a first-in-class translational medicine institute dedicated to advancing life sciences in the race to eliminate disease and improve human health and life.

By connecting early-stage biotech companies with cutting-edge life science discoveries —and backed by the mission and resources of industry leaders, investors, and philanthropic partners—IBRI is successfully evolving a new, independent model to conquer disease, uniting previously fragmented forces in the quest for cures.

Carefully curating and supporting early-stage companies with investment, talent, and space, IBRI strategically accelerates drug discovery. Our work benefits from the relatively low cost of living and doing business here, allowing more resources to be directed toward science.

Fueled by the same entrepreneurial creativity as the groundbreaking scientific work we support, IBRI’s labs advance research across the frontiers of diabetes, metabolic disease, Alzheimer’s disease, and rare pediatric diseases. Our ambitious public–private vision cultivates talent while efficiently bridging the gap between research-driven inquiry and profit-driven drug development.

At IBRI, cures are launched on a clear pathway to clinical trials, enabled by the combined resources and experience of our academic and industry partners, without the typical pressure to deliver rapid results for commercialization. IBRI labs pursue breakthroughs that might never happen elsewhere. Breakthroughs are happening here. Our novel financing model ensures that when discoveries are ready for clinical trials, the intellectual property is sold back to industry or spun off, creating a direct stream of revenue.

By every measure, the IBRI model demonstrates a novel approach that delivers rewards. Scientific bench work is nurtured, drug discovery is advanced, workforce development is continuous, investors see returns, and donors see impact. Most importantly, IBRI’s structure and portfolio of accomplishments matter to the patients whose lives are improved—or even saved—by this forward-looking approach to life sciences.

IBRI is driven to bring next-generation therapies to market with an understanding of the complex pressures that often bind innova0on to economics. After more than a decade, the evidence is clear: IBRI is poised to transform life sciences—and for millions of people, even life itself.